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Dr. Sherman Silber has been a world leader in In Vitro Fertilization for over 35 years.

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Send an email to our staff with any questions and get a quick reply to your concerns! Are you ready to take the next step?

IVF Treatment for Women Over 40

Women who are over 38 years of age often have very few eggs and respond poorly to conventional ovarian stimulation, and because of lower pregnancy rates, are often just cancelled by IVF clinics for fear that such cases will lower their reportable statistics. Such patients also usually require huge doses of expensive drugs that can add another $6,000 to the already high cost of conventional IVF.

While one option is using donor eggs, many women prefer getting pregnant using their own eggs. The best solution for these patients is the Japanese mini-IVF, using a specialized pure-air environment, along with an absolutely safe and reliable system for embryo freezing.


Read about how Dr. Silber makes IVF such a simple process.


Mini-IVF is a revolutionary procedure that costs less and is virtually painless.

The Moment of Conception

Watch as Dr. Silber successfully performs an embryo transfer.

Success of Dr. Silber’s Procedure

Mini-IVF, first developed by the Kato Ladies Clinic in Japan and then perfected and popularized at St. Luke’s Hospital in St. Louis, is the right approach for women over 40 or women with low ovarian reserve who still want to use their own rather than donor eggs.

The success of this approach depends not only on a novel endocrine stimulation protocol, but also upon a flawless method of embryo freezing such as our vitrification system, and the highest level laboratory air purification system to give the eggs from women over 40 the best possible environment in which to develop.

Dr. Silber Performs IVF Live

Click to watch Dr. Silber perform a live IVF on the “Today” Show.


The Today Show

Discovery Health

“Infertile couples from all over the world come to St. Louis, Missouri, to chase their dream, because Dr. Sherman Silber and his team are simply the best there is.”


Vasectomy Reversals

Learn about vasectomy reversals and how Dr. Silber is so successful.

Freezing the Biological Clock

Watch the video discussing the new techniques for preserving a woman’s fertility indefinitely – Channel 11 St. Louis

Patient Comments

“Other doctors said we should begin looking into adoption. Thanks to Dr. Silber, Connor was born on May 16, 2012.” – Chris & Kim Blase


Learn about the cost savings with advanced technology.