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Infertile patients cannot afford to wait for treatment while their eggs get older.

Dr. Sherman Silber, Infertility Center of St. Louis, is offering video consultations for patients who need to plan now for their treatment while stay-at-home orders are in place. He is talking to and evaluating patients in their home to comply with social distancing measures.

Dr. Silber is discovering that patients actually prefer this method of telemedicine consultation over the conventional office visit. Patients have conveyed that “it is so much more convenient and less stressful” to have a telemedicine personal consultation than to take a day off from work to travel to the doctor’s office and sit with other nervous patients in the waiting room.

The COVID-19 pandemic is thus changing much of the way we will do things in the future, and for the better. “Our patients are surprisingly much happier with this approach. Of course, at some point we need to perform hands on treatment. But with this new manner of seeing patients, we can come to the right diagnosis and treatment plan for most patients more efficiently, quickly, and painlessly, with no loss of personal one-on-one communication.” This is a very welcome new era of telemedicine that has been forced on us by the current difficult times.

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The Infertility Center of St. Louis
The Infertility Center of St. Louis
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Over-40 Mini-IVF Success: Rajeev & Zakiya with Dr. Sherman Silber (Facebook Live)

In this Facebook Live, Dr. Sherman J. Silber interviews Rajeev and Hope, a Wisconsin couple who conceived at the Infertility Center of St. Louis after multiple failed IVF cycles elsewhere. At two prior clinics, they endured very high-dose stimulation (8–9 drug types, twice-daily injections for weeks) and costly “genetic testing” (PGT-A) that labeled every embryo abnormal, leading to hard-sell donor-egg quotes. Discouraged, they researched alternatives and found patient testimonials pointing to Dr. Silber’s Mini-IVF approach.

Dr. Silber explains four pillars of his protocol: (1) Minimal FSH (e.g., ~150 IU every other day) to recruit the best cohort rather than “frying” eggs with mega-doses; (2) Endogenous LH support (via clomiphene) instead of menopur-heavy regimens that can induce apoptosis; (3) Prevent premature ovulation by staying on clomiphene rather than full antagonist shutdown; (4) Cycle priming with birth-control pills to synchronize follicles before gentle stimulation. The clinic also performs ICSI on all cycles (no extra fee), practices freeze-all with vitrification, favors day-3 embryo cryo (higher baby-per-egg yield across 14,000 cycles), and schedules transfer months later in an optimized uterine environment.

Hope—41 at retrievals, 42 at delivery—describes the contrast: at St. Louis she used just clomiphene plus a low FSH micro-dose and an hCG trigger, producing four mature eggs and four good embryos on the first Mini-IVF round, with rapid lab feedback and highly responsive coordination (shout-out to Kelsey). After the first transfer failed, the second succeeded; their daughter “Hope” is the result. Dr. Silber cautions that routine PGT-A can misclassify viable embryos (while mutation-specific testing remains valuable) and notes typical outcomes: for a 34-year-old, ~60% live birth per transfer and ~97% likelihood after three transfers if enough embryos are banked. He emphasizes Mini-IVF for low ovarian reserve and critiques private-equity clinic incentives.

The session closes with practical FAQs (time commitment, meds, storage fees—all included in a single set fee) and an invitation for free consultations.