A Hopeful Breakthrough for Turner’s Syndrome Patients ST. LOUIS MISSOURI, October 2, 2023 In a groundbreaking medical milestone, a team of researchers has successfully performed the world’s first ovary tissue allotransplantation to a Turner’s syndrome patient resulting in a successful pregnancy, offering hope to thousands of women who have long faced fertility challenges due to […]
By: Sherman J. Silber, Sierra Goldsmith, Leilani Castleman, Kellie Hurlbut, Yuting Fan, Jeffery Melnick, Katsuhiko Hayashi Download Full PDF Article Abstract Research question Is it possible to use experience gained from 24 years of frozen ovarian transplantation, and from recent experience with in-vitro gametogenesis to accomplish simple and robust in-vitro maturation (IVM) of oocytes from […]
By: Erica C. Pandolfi, Ernesto J. Rojas, Enrique Sosa, Joanna J. Gell, Timothy J. Hunt, Sierra Goldsmith, Yuting Fan, Sherman J. Silber Amander T. Clark Download PDF Version Abstract We generated three human induced pluripotent stem cell (hiPSC) sublines from human dermal fibroblasts (HDFs) (MZT04) generated from a skin biopsy donated from a previously fertile […]
By: Erica C. Pandolfi, Enrique Sosa, Timothy J. Hunt, Sierra Goldsmith, Kellie Hurlbut, Sherman J. Silber, Amander T. Clark Download PDF version Abstract Six human induced pluripotent stem cell sublines (hiPSCs) were generated from human dermal fibroblasts (HDFs) derived from skin biopsies donated from monozygotic twin women wherein one woman had proven fertility and her […]
By: Erica C. Pandolfi, Timothy J. Hunt, Sierra Goldsmith, Kellie Hurlbut, Sherman J. Silber, Amander T. Clark July 2021 Download PDF version Abstract We generated three human induced pluripotent stem cell (hiPSC) sublines from human dermal fibroblasts (HDF) (MZT05) generated from a skin biopsy donated from a previously fertile woman. The skin biopsy was broadly […]
Extract from December 6th, 2019 The New York Times Article about Dr. Silber’s Pioneering Microsurgery A 36-year-old man born without testicles received one transplanted from his identical twin brother in a six-hour operation performed on Tuesday in Belgrade, Serbia, by an international team of surgeons. The operation was only the third known transplant of this […]
By: John Zhang, Hui Liu, Shiyu Luo, Zhuo Lu, Alejandro Chávez-Badiola, Zitao Liu, Mingxue Yang, Zaher Merhi, Sherman J Silber, Santiago Munné, Michalis Konstandinidis, Dagan Wells, Taosheng Huang January 31, 2017 Download PDF version of this chapter Introduction Mutations in mitochondrial DNA (mtDNA) are maternally inherited and can cause fatal or debilitating mitochondrial disorders. The […]
Rob Stein E-mail address: silber@infertile.com (Sherman Silber). NPR, Morning Edition, July 19, 2016 Download the PDF Version of this Article Dr. Sherman Silber, a renowned pioneer in microsurgery and infertility, is considered one of the world’s leading authorities on IVF, sperm retrieval, ICSI, vasectomy reversal, male infertility, Y chromosome, tubal ligation reversal, egg and embryo […]
By Clare Wilson, New Scientist Download PDF version of Clare Wilson’s Article Introduction Freezing an ovary and then having thin slices of it periodically put back in looks set to offer women a way to delay or reverse menopause. It could be as revolutionary as the pill. Freezing an ovary and having thin slices of […]
How ovarian transplantation works and how resting follicle recruitment occurs: A Review of Results Reported From One Center By SHERMAN SILBER Women’s Health Download PDF version of Dr. Silber’s Article in Women’s Health Magazine Summary Ovarian freezing and transplantation has garnered increasing interest as a potential way of preserving fertility in cancer patients. This special report […]
Transplantation of ovarian tissue or immature oocytes to preserve and restore fertility in humans By SHERMAN SILBER Biology and Pathology of the Oocyte: Role in Fertility, Medicine and Nuclear Reprograming, Natalie Barbey and David Silber, June 24, 2013 Download PDF version of this chapter Introduction It is now possible to preserve and restore fertility, using […]
Ovarian tissue vitrification—Clinical realities and outcomes By SHERMAN SILBER Vitrification in Assisted Reproduction, Second Edition Edited by Michael J. Tucker, PhD, FIboil, HCLD(AAB) & Juergen Liebermann, PhD, HCLD(AAB) Download PDF version of Dr. Silber’s Chapter Download PDF version of the Foreword Download PDF version of the Title Page PrefaceThe developed world is in the midst of […]