You can call us at 314-576-1400 or email us for a free, immediate, and personal telemedicine consultation with Dr. Silber. read more

Infertile patients cannot afford to wait for treatment while their eggs get older.

Dr. Sherman Silber, Infertility Center of St. Louis, is offering free video consultations for patients who need to plan now for their treatment while stay-at-home orders are in place. He is talking to and evaluating patients in their home to comply with social distancing measures.

Dr. Silber is discovering that patients actually prefer this method of telemedicine consultation over the conventional office visit. Patients have conveyed that “it is so much more convenient and less stressful” to have a free telemedicine personal consultation than to take a day off from work to travel to the doctor’s office and sit with other nervous patients in the waiting room.

The COVID-19 pandemic is thus changing much of the way we will do things in the future, and for the better. “Our patients are surprisingly much happier with this approach. Of course, at some point we need to perform hands on treatment. But with this new manner of seeing patients, we can come to the right diagnosis and treatment plan for most patients more efficiently, quickly, and painlessly, with no loss of personal one-on-one communication.” This is a very welcome new era of telemedicine that has been forced on us by the current difficult times.

News Category: Scientific Papers

In-vitro maturation and transplantation of cryopreserved ovary tissue: understanding ovarian longevity

By: Sherman J. Silber, Sierra Goldsmith, Leilani Castleman, Kellie Hurlbut, Yuting Fan, Jeffery Melnick, Katsuhiko Hayashi Download Full PDF Article Abstract Research question Is it possible to use experience gained from 24 years of frozen ovarian transplantation, and from recent experience with in-vitro gametogenesis to accomplish simple and robust in-vitro maturation (IVM) of oocytes from […]

Generation of three human induced pluripotent stem cell sublines (MZT04D, MZT04J, MZT04C) for reproductive science research

By: Erica C. Pandolfi, Ernesto J. Rojas, Enrique Sosa, Joanna J. Gell, Timothy J. Hunt, Sierra Goldsmith, Yuting Fan, Sherman J. Silber Amander T. Clark Download PDF Version Abstract We generated three human induced pluripotent stem cell (hiPSC) sublines from human dermal fibroblasts (HDFs) (MZT04) generated from a skin biopsy donated from a previously fertile […]

Generation of six human induced pluripotent stem cell sublines (MZT01E, MZT01F, MZT01N and MZT02D, MZT02G and MZT02H) for reproductive science research

By: Erica C. Pandolfi, Enrique Sosa, Timothy J. Hunt, Sierra Goldsmith, Kellie Hurlbut, Sherman J. Silber, Amander T. Clark Download PDF version Abstract Six human induced pluripotent stem cell sublines (hiPSCs) were generated from human dermal fibroblasts (HDFs) derived from skin biopsies donated from monozygotic twin women wherein one woman had proven fertility and her […]

Generation of three human induced pluripotent stem cell sublines (UCLAi005-A, UCLAi005-B and UCLAi005-C) for reproductive science research

By: Erica C. Pandolfi, Timothy J. Hunt, Sierra Goldsmith, Kellie Hurlbut, Sherman J. Silber, Amander T. Clark July 2021 Download PDF version Abstract We generated three human induced pluripotent stem cell (hiPSC) sublines from human dermal fibroblasts (HDF) (MZT05) generated from a skin biopsy donated from a previously fertile woman. The skin biopsy was broadly […]

Live Birth Derived From Oocyte Spindle Transfer To Prevent Mitochondrial Disease

By: John Zhang, Hui Liu, Shiyu Luo, Zhuo Lu, Alejandro Chávez-Badiola, Zitao Liu, Mingxue Yang, Zaher Merhi, Sherman J Silber, Santiago Munné, Michalis Konstandinidis, Dagan Wells, Taosheng Huang January 31, 2017 Download PDF version of this chapter Introduction Mutations in mitochondrial DNA (mtDNA) are maternally inherited and can cause fatal or debilitating mitochondrial disorders. The […]

Women’s Health Article – How Ovarian Transplantation Works

How ovarian transplantation works and how resting follicle recruitment occurs: A Review of Results Reported From One Center By SHERMAN SILBER Women’s Health Download PDF version of Dr. Silber’s Article in Women’s Health Magazine Summary Ovarian freezing and transplantation has garnered increasing interest as a potential way of preserving fertility in cancer patients.  This special report […]

Chapter by Dr. Silber in Medical Textbook: Biology of the Oocyte

Transplantation of ovarian tissue or immature oocytes to preserve and restore fertility in humans By SHERMAN SILBER Biology and Pathology of the Oocyte: Role in Fertility, Medicine and Nuclear Reprograming, Natalie Barbey and David Silber, June 24, 2013 Download PDF version of this chapter   Introduction It is now possible to preserve and restore fertility, using […]

Chapter by Dr. Silber in Textbook: Vitrification in Assisted Reproduction

Ovarian tissue vitrification—Clinical realities and outcomes By SHERMAN SILBER Vitrification in Assisted Reproduction, Second Edition Edited by Michael J. Tucker, PhD, FIboil, HCLD(AAB) & Juergen Liebermann, PhD, HCLD(AAB) Download PDF version of Dr. Silber’s Chapter Download PDF version of the Foreword Download PDF version of the Title Page PrefaceThe developed world is in the midst of […]

Chapter on Human Ovarian Tissue Vitrification

Human Ovarian Tissue Vitrification By SHERMAN SILBER Cryopreservation of Mammalian Gametes and Embryos: Methods and Protocols, Ashok Agarwal, Zsolt Peter Nagy and Alex Varghese June 24, 2013 Download PDF version of this chapter Summary Ovarian freezing and transplantation has garnered increasing interest as a potential way of preserving fertility in cancer patients as well as […]

Unexpected resilience of species with temperature-dependent sex determination at the Cretaceous–Palaeogene boundary – Biology Letters

S. Silber1,*, Jonathan H. Geisler2 and Minjin Bolortsetseg3 1 Infertility Center of Saint Louis, St Luke’s Hospital, Saint Louis, MO 63017, USA 2New York College of Osteopathic Medicine, Old Westbury, NY 11568, USA 3Institute for the Study of Mongolian Dinosaurs, Ulaanbaatar 14201, Mongolia *Author for correspondence (sharon@infertile.com). Biology Letters, October 27, 2010 Download PDF version […]

Human Male Infertility, the Y Chromosome, and Dinosaur Extinction – Middle East Fertility Society Journ

Sherman Silber Infertility Center of St. Louis, St. Luke’s Hospital, St. Louis, MissouriAcademic Medical Center (AMC), Amsterdam, The Netherlands Middle East Fertility Society Journal, January 18, 2011 Download PDF version of this article Study of the molecular genetics of human male infertility and the Y chromosome has helped to elucidate the evolution of our X […]

Sperm retrieval for azoospermia and intracytoplasmic sperm injection success rates – A personal overview

Dr. Sherman J. Silber of The Infertility Center of Saint Louis, St Luke’s Hospital, Saint Louis, MO 63017, USAHuman Fertility – December 2010 Abstract It is often questioned whether sperm parameters, including whether retrieved or ejaculated, have any effect on intracytoplasmic sperm injection (ICSI) results. Do severe spermatogenic defects affect embryo quality or pregnancy rate? […]

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